Research Studies

Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival.

Cannabis species and cannabinoid concentration preference among sleep-disturbed medicinal cannabis users.

Fibromyalgia Patients Rate Marijuana Significantly More Effective Than FDA-Approved Drugs

Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.

Marijuana and Migraines.

Cannabinoids for gastrointestinal diseases: potential therapeutic applications.

Clinical evaluation and optimal management of cancer cachexia.

Cannabis Use in HIV for Pain and Other Medical Symptoms.

Neuroprotective effect of cannabidiol.

Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ⁹-THCV in animal models of Parkinson’s disease.

Low-dose vaporized cannabis significantly improves neuropathic pain.

Cannabidiol–antiepileptic drug comparisons and interactions in experimentally induced seizures in rats.

Cannabinoids: novel therapies for arthritis?

Cannabinoids in glaucoma: a primary screening procedure.

Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis.

Cannabinoids and neuroprotection in motor-related disorders.

Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice.

Antitumor Effects of Cannabidiol, a Nonpsychoactive Cannabinoid, on Human Glioma Cell Lines.

Δ9-Tetrahydrocannabinol alone and combined with cannabidiol mitigate fear memory through reconsolidation disruption.

Cannabis effective at relieving pain after major surgery.

Cannabis Use in Patients with Fibromyalgia: Effect on Symptoms Relief and Health-Related Quality of Life.

Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?

Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?

Selective inhibition of FAAH produces antidiarrheal and antinociceptive effect mediated by endocannabinoids and cannabinoid-like fatty acid amides.

Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpesvirus-infected endothelium.

Effects of cannabidiol in the treatment of patients with Parkinson’s disease: an exploratory double-blind trial.

Muscular dystrophy in mice after chronic subcutaneous treatment with cannabinoids.

Involvement of the endocannabinoid system in osteoarthritis pain.

Effects of tetrahydrocannabinol on arterial and intraocular hypertension.

Delta-9-THC in the treatment of spasticity associated with multiple sclerosis.

Cannabis induces a clinical response in patients with Crohn’s disease: a prospective placebo-controlled study.

The Combination of Cannabidiol and Δ9-Tetrahydrocannabinol Enhances the Anticancer Effects of Radiation in an Orthotopic Murine Glioma Model.

Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: a positron emission tomography study.

Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action.

Medical marijuana in neurology.

Cannabis in painful HIV-associated sensory neuropathy.

A Molecular Link Between the Active Component of Marijuana and Alzheimer’s Disease Pathology.

Cannabidiol for the treatment of psychosis in Parkinson’s disease.

Cannabinoids and the immune system: potential for the treatment of inflammatory diseases?

Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study.

Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival.

A pilot clinical study of Δ9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme.

Cannabis use among military veterans after residential treatment for posttraumatic stress disorder.

The effectiveness of cannabinoids in the management of chronic nonmalignant neuropathic pain: a systematic review.

The medicinal use of cannabis and cannabinoids–an international cross-sectional survey on administration forms.

Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation.

Smoked Medicinal Cannabis for Neuropathic Pain in HIV: A Randomized, Crossover Clinical Trial.

Cannabinoids for treatment of Alzheimer’s disease: moving toward the clinic.

Potential Role of Cannabinoids in Parkinson’s Disease.

Perceived efficacy of cannabidiol-enriched cannabis extracts for treatment of pediatric epilepsy: A potential role for infantile spasms and Lennox-Gastaut syndrome.

Expression of cannabinoid receptor 2 and its inhibitory effects on synovial fibroblasts in rheumatoid arthritis.

Medical Marijuana in Certain Neurological Disorders.

Cannabis and amyotrophic lateral sclerosis.

Cannabidiol inhibits angiogenesis by multiple mechanisms.

Cannabinoids in the management of difficult to treat pain.

Association of herbal cannabis use with negative psychosocial parameters in patients with fibromyalgia.

Smoked cannabis for chronic neuropathic pain: a randomized controlled trial.

Cannabis for migraine treatment: the once and future prescription? An historical and scientific review.

The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus.

Cannabis (medical marijuana) treatment for motor and non-motor symptoms of Parkinson disease: an open-label observational study.

Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy.

Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.

The Composition of Hemp Seed Oil and Its Potential as an Important Source of Nutrition.

Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms.

THCV: The Sports Car of Cannabinoids.

Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid.

Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration.

Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation.

Antitumor effects of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell lines.

Turning Over a New Leaf: Cannabinoid and Endocannabinoid Modulation of Immune Function.

A cannabigerol quinone alleviates neuroinflammation in a chronic model of multiple sclerosis.

Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ(9)-tetrahydrocannabinol.

Cannabidivarin is anticonvulsant in mouse and rat.

Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo.

CBN: A Sleeping Synergy.

A cannabigerol derivative suppresses immune responses and protects mice from experimental autoimmune encephalomyelitis.

Biological activity of cannabichromene, its homologs and isomers.

Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression.

Tetrahydrocannabinol for treatment of chronic pain.

Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.

Pharmacologic interaction between cannabinol and delta9-tetrahydrocannabinol.

Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ9-THCV in animal models of Parkinson’s disease.

Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects.

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes.

Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews.

The effect of cannabichromene on adult neural stem/progenitor cells.

Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV) and Δ(9) -tetrahydrocannabivarin (THCV), to produce CB1 receptor inverse agonism symptoms of nausea in rats.

Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease.

Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression.

Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid.

Nutritional Interventions for Cancer-induced cachexia.

Effects of Smoked Cannabis and Oral δ9-Tetrahydrocannabinol on Nausea and Emesis After Cancer Chemotherapy.

Cannabis to relieve post-op pain.

Persistent post-operative pain.

Complementary and Alternative Medicine for Glaucoma.

Marijuana Smoking vs Cannabinoids for Glaucoma Therapy.

Acute activation of cannabinoid receptors by anandamide reduces gastrointestinal motility and improves postprandial glycemia in mice.

Comprehensive Review of Medicinal Marijuana, Cannabinoids, and Therapeutic Implications in Medicine and Headache: What a Long Strange Trip It’s Been.

The endocannabinoid system: physiology and pharmacology.

AAH‐fetched approach to treat osteoarthritis pain.

Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy.